Date Name Title Filing Type Shares Traded Price Total Held
Dec 18, 2006
VP, Regulatory Development
VP, Regulatory Development Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 4,966 -- 4,966
Dec 18, 2006
VP, Regulatory Development
VP, Regulatory Development Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 25,034 -- 25,034
Dec 18, 2006
SVP, Manufuring Operations
SVP, Manufuring Operations Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 4,921 -- 4,921
Dec 18, 2006
SVP, Manufuring Operations
SVP, Manufuring Operations Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 70,079 -- 70,079
Dec 18, 2006
Director, Chief Exec Officer & President, Ten Percent Owner
Director, Chief Exec Officer & President, Ten Percent Owner Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 250,000 -- 250,000
Dec 18, 2006
SVP, Therap & Clin Prog Dev
SVP, Therap & Clin Prog Dev Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 4,921 -- 4,921
Dec 18, 2006
SVP, Therap & Clin Prog Dev
SVP, Therap & Clin Prog Dev Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 95,079 -- 95,079
Dec 18, 2006
Director
Director Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 4,921 -- 4,921
Dec 18, 2006
Director
Director Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 307,579 -- 307,579
Dec 18, 2006
Director, EVP, CSO, & Pres Regn Res Labs
Director, EVP, CSO, & Pres Regn Res Labs Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 4,921 -- 4,921

* Represents the number of non-derivative securities directly held. (I) Indicates that some (or all) of these shares are held indirectly.