Date Name Title Filing Type Shares Traded Price Total Held
Dec 09, 2022
EVP Research and Development
EVP Research and Development Form 4 Payment of exercise price or tax liability by delivering or withholding securities incident to the receipt, exercise or vesting of a security issued in accordance with Rule 16b-3 466 $753.28 51,999
Nov 08, 2022
EVP Research and Development
EVP Research and Development Form 4 Bona fide gift 330 -- 52,465
Aug 08, 2022
EVP Research and Development
EVP Research and Development Form 4 Other acquisition or disposition -- -- 5,814
Aug 08, 2022
EVP Research and Development
EVP Research and Development Form 4 Other acquisition or disposition -- -- 4,605
Aug 05, 2022
EVP Research and Development
EVP Research and Development Form 4 Open market or private sale of non-derivative or derivative security 176 $606.78 76,401
Aug 05, 2022
EVP Research and Development
EVP Research and Development Form 4 Open market or private sale of non-derivative or derivative security 724 $607.47 75,677
Aug 05, 2022
EVP Research and Development
EVP Research and Development Form 4 Open market or private sale of non-derivative or derivative security 610 $608.70 75,067
Aug 05, 2022
EVP Research and Development
EVP Research and Development Form 4 Open market or private sale of non-derivative or derivative security 3,044 $609.62 72,023
Aug 05, 2022
EVP Research and Development
EVP Research and Development Form 4 Open market or private sale of non-derivative or derivative security 3,931 $610.49 68,092
Aug 05, 2022
EVP Research and Development
EVP Research and Development Form 4 Open market or private sale of non-derivative or derivative security 2,022 $611.44 66,070

* Represents the number of non-derivative securities directly held. (I) Indicates that some (or all) of these shares are held indirectly.