Date Name Title Filing Type Shares Traded Price Total Held
Dec 14, 2012
SVP Res and Devel Sciences
SVP Res and Devel Sciences Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 112,500 -- 112,500
Jan 05, 2005
SVP, PreclinDevel & Biomol Sci
SVP, PreclinDevel & Biomol Sci Form 4 Disposition to the issuer of issuer equity securities pursuant to Rule 16b-3(e) 100,000 -- --
Dec 17, 2007
SVP, Research & Devel Sciences
SVP, Research & Devel Sciences Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 95,438 -- 95,438
Jun 18, 2012
SVP Res & Dev Sciences
SVP Res & Dev Sciences Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 95,079 $20.32 154,200
Jun 18, 2012
SVP Res & Dev Sciences
SVP Res & Dev Sciences Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 95,079 -- --
Dec 18, 2006
SVP, Therap & Clin Prog Dev
SVP, Therap & Clin Prog Dev Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 95,079 -- 95,079
Aug 04, 2022
EVP Research and Development
EVP Research and Development Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 95,000 $270.43 147,795
Aug 04, 2022
EVP Research and Development
EVP Research and Development Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 95,000 -- --
Dec 13, 2013
SVP Research and Development S
SVP Research and Development S Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 95,000 -- 95,000
Jan 05, 2005
SVP, PreclinDevel & Biomol Sci
SVP, PreclinDevel & Biomol Sci Form 4 Disposition to the issuer of issuer equity securities pursuant to Rule 16b-3(e) 94,851 -- --

* Represents the number of non-derivative securities directly held. (I) Indicates that some (or all) of these shares are held indirectly.