Date Name Title Type Shares Traded Price
Dec 18, 2006
SVP, Therap & Clin Prog Dev
SVP, Therap & Clin Prog Dev Grant, award or other acquisition pursuant to Rule 16b-3(d) 4,921 --
Dec 18, 2006
SVP, Therap & Clin Prog Dev
SVP, Therap & Clin Prog Dev Grant, award or other acquisition pursuant to Rule 16b-3(d) 95,079 --
Nov 01, 2006
SVP, Therap & Clin Prog Dev
SVP, Therap & Clin Prog Dev Open market or private sale of non-derivative or derivative security 5,760 $20.00
Oct 31, 2006
SVP, Therap & Clin Prog Dev
SVP, Therap & Clin Prog Dev Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 18,311 $10.56
Oct 31, 2006
SVP, Therap & Clin Prog Dev
SVP, Therap & Clin Prog Dev Payment of exercise price or tax liability by delivering or withholding securities incident to the receipt, exercise or vesting of a security issued in accordance with Rule 16b-3 9,612 $20.12
Oct 31, 2006
SVP, Therap & Clin Prog Dev
SVP, Therap & Clin Prog Dev Payment of exercise price or tax liability by delivering or withholding securities incident to the receipt, exercise or vesting of a security issued in accordance with Rule 16b-3 2,939 $20.12
Oct 31, 2006
SVP, Therap & Clin Prog Dev
SVP, Therap & Clin Prog Dev Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 24,226 $10.56
Oct 31, 2006
SVP, Therap & Clin Prog Dev
SVP, Therap & Clin Prog Dev Open market or private sale of non-derivative or derivative security 24,226 $20.00
Oct 31, 2006
SVP, Therap & Clin Prog Dev
SVP, Therap & Clin Prog Dev Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 3,100 $10.56
Oct 31, 2006
SVP, Therap & Clin Prog Dev
SVP, Therap & Clin Prog Dev Open market or private sale of non-derivative or derivative security 3,100 $20.01

* Represents the number of non-derivative securities directly held. (I) Indicates that some (or all) of these shares are held indirectly.