Date Name Title Filing Type Shares Traded Price Total Held
Dec 18, 2006
SVP, Therap & Clin Prog Dev
SVP, Therap & Clin Prog Dev Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 4,921 -- 4,921
Dec 18, 2006
SVP, Therap & Clin Prog Dev
SVP, Therap & Clin Prog Dev Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 95,079 -- 95,079
Nov 01, 2006
SVP, Therap & Clin Prog Dev
SVP, Therap & Clin Prog Dev Form 4 Open market or private sale of non-derivative or derivative security 5,760 $20.00 3,887
Oct 31, 2006
SVP, Therap & Clin Prog Dev
SVP, Therap & Clin Prog Dev Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 18,311 $10.56 22,198
Oct 31, 2006
SVP, Therap & Clin Prog Dev
SVP, Therap & Clin Prog Dev Form 4 Payment of exercise price or tax liability by delivering or withholding securities incident to the receipt, exercise or vesting of a security issued in accordance with Rule 16b-3 9,612 $20.12 12,586
Oct 31, 2006
SVP, Therap & Clin Prog Dev
SVP, Therap & Clin Prog Dev Form 4 Payment of exercise price or tax liability by delivering or withholding securities incident to the receipt, exercise or vesting of a security issued in accordance with Rule 16b-3 2,939 $20.12 9,647
Oct 31, 2006
SVP, Therap & Clin Prog Dev
SVP, Therap & Clin Prog Dev Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 24,226 $10.56 33,873
Oct 31, 2006
SVP, Therap & Clin Prog Dev
SVP, Therap & Clin Prog Dev Form 4 Open market or private sale of non-derivative or derivative security 24,226 $20.00 9,647
Oct 31, 2006
SVP, Therap & Clin Prog Dev
SVP, Therap & Clin Prog Dev Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 3,100 $10.56 12,747
Oct 31, 2006
SVP, Therap & Clin Prog Dev
SVP, Therap & Clin Prog Dev Form 4 Open market or private sale of non-derivative or derivative security 3,100 $20.01 9,647

* Represents the number of non-derivative securities directly held. (I) Indicates that some (or all) of these shares are held indirectly.