Date Name Title Filing Type Shares Traded Price Total Held
Oct 31, 2006
SVP, Therap & Clin Prog Dev
SVP, Therap & Clin Prog Dev Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 900 $10.56 10,547
Oct 31, 2006
SVP, Therap & Clin Prog Dev
SVP, Therap & Clin Prog Dev Form 4 Open market or private sale of non-derivative or derivative security 900 $20.02 9,647
Oct 31, 2006
SVP, Therap & Clin Prog Dev
SVP, Therap & Clin Prog Dev Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 115 $10.56 9,762
Oct 31, 2006
SVP, Therap & Clin Prog Dev
SVP, Therap & Clin Prog Dev Form 4 Open market or private sale of non-derivative or derivative security 115 $20.03 9,647
Oct 31, 2006
SVP, Therap & Clin Prog Dev
SVP, Therap & Clin Prog Dev Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 100 $10.56 9,747
Oct 31, 2006
SVP, Therap & Clin Prog Dev
SVP, Therap & Clin Prog Dev Form 4 Open market or private sale of non-derivative or derivative security 100 $20.04 9,647
Oct 31, 2006
SVP, Therap & Clin Prog Dev
SVP, Therap & Clin Prog Dev Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 300 $10.56 9,947
Oct 31, 2006
SVP, Therap & Clin Prog Dev
SVP, Therap & Clin Prog Dev Form 4 Open market or private sale of non-derivative or derivative security 300 $20.05 9,647
Oct 31, 2006
SVP, Therap & Clin Prog Dev
SVP, Therap & Clin Prog Dev Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 700 $10.56 10,347
Oct 31, 2006
SVP, Therap & Clin Prog Dev
SVP, Therap & Clin Prog Dev Form 4 Open market or private sale of non-derivative or derivative security 700 $20.06 9,647

* Represents the number of non-derivative securities directly held. (I) Indicates that some (or all) of these shares are held indirectly.