Date Name Title Filing Type Shares Traded Price Total Held
Oct 31, 2006
SVP, Therap & Clin Prog Dev
SVP, Therap & Clin Prog Dev Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 200 -- 2,048
Oct 31, 2006
SVP, Therap & Clin Prog Dev
SVP, Therap & Clin Prog Dev Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 1,400 -- 648
Oct 31, 2006
SVP, Therap & Clin Prog Dev
SVP, Therap & Clin Prog Dev Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 200 -- 448
Oct 31, 2006
SVP, Therap & Clin Prog Dev
SVP, Therap & Clin Prog Dev Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 400 -- 48
Oct 31, 2006
SVP, Therap & Clin Prog Dev
SVP, Therap & Clin Prog Dev Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 48 -- --
Oct 31, 2006
SVP, Therap & Clin Prog Dev
SVP, Therap & Clin Prog Dev Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 18,311 -- --
Dec 17, 2008
SVP, Research & Devel Sciences
SVP, Research & Devel Sciences Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 5,952 -- 5,952
Dec 17, 2008
SVP, Research & Devel Sciences
SVP, Research & Devel Sciences Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 44,048 -- 44,048
Oct 01, 2008
SVP, Research & Devel Sciences
SVP, Research & Devel Sciences Form 4 Other acquisition or disposition -- -- 4,275
Sep 30, 2008
SVP, Research & Devel Sciences
SVP, Research & Devel Sciences Form 4 Open market or private sale of non-derivative or derivative security 200 $21.66 10,467

* Represents the number of non-derivative securities directly held. (I) Indicates that some (or all) of these shares are held indirectly.