Date Name Title Type Shares Traded Price
Aug 04, 2022
EVP Research and Development
EVP Research and Development Payment of exercise price or tax liability by delivering or withholding securities incident to the receipt, exercise or vesting of a security issued in accordance with Rule 16b-3 71,218 $613.00
May 14, 2021
EVP Research and Development
EVP Research and Development Payment of exercise price or tax liability by delivering or withholding securities incident to the receipt, exercise or vesting of a security issued in accordance with Rule 16b-3 27,775 $516.69
May 14, 2021
EVP Research and Development
EVP Research and Development Payment of exercise price or tax liability by delivering or withholding securities incident to the receipt, exercise or vesting of a security issued in accordance with Rule 16b-3 7,204 $516.69
May 08, 2020
EVP Research and Development
EVP Research and Development Payment of exercise price or tax liability by delivering or withholding securities incident to the receipt, exercise or vesting of a security issued in accordance with Rule 16b-3 7,195 $560.67
Apr 13, 2020
EVP Research and Development
EVP Research and Development Payment of exercise price or tax liability by delivering or withholding securities incident to the receipt, exercise or vesting of a security issued in accordance with Rule 16b-3 7,582 $511.56
Feb 26, 2020
EVP Research and Development
EVP Research and Development Payment of exercise price or tax liability by delivering or withholding securities incident to the receipt, exercise or vesting of a security issued in accordance with Rule 16b-3 14,651 $451.89
Feb 12, 2020
EVP Research and Development
EVP Research and Development Payment of exercise price or tax liability by delivering or withholding securities incident to the receipt, exercise or vesting of a security issued in accordance with Rule 16b-3 14,722 $402.34
Nov 25, 2019
EVP Research and Development
EVP Research and Development Payment of exercise price or tax liability by delivering or withholding securities incident to the receipt, exercise or vesting of a security issued in accordance with Rule 16b-3 5,994 $362.75
May 13, 2019
EVP Research and Development
EVP Research and Development Payment of exercise price or tax liability by delivering or withholding securities incident to the receipt, exercise or vesting of a security issued in accordance with Rule 16b-3 15,147 $304.20
May 23, 2018
EVP Research and Development
EVP Research and Development Payment of exercise price or tax liability by delivering or withholding securities incident to the receipt, exercise or vesting of a security issued in accordance with Rule 16b-3 15,329 $293.68

* Represents the number of non-derivative securities directly held. (I) Indicates that some (or all) of these shares are held indirectly.