Date Name Title Filing Type Shares Traded Price Total Held
Aug 17, 2021
Director, President and Chief Scientific
Director, President and Chief Scientific Form 4 Other acquisition or disposition -- -- 213,693
Feb 06, 2023
Director, President and Chief Scientific
Director, President and Chief Scientific Form 4 Open market or private sale of non-derivative or derivative security 13,189 $800.08 200,504
Feb 08, 2023
Director, President and Chief Scientific
Director, President and Chief Scientific Form 4 Other acquisition or disposition -- -- 569,653
Feb 08, 2023
Director, President and Chief Scientific
Director, President and Chief Scientific Form 4 Other acquisition or disposition -- -- 5,869
Feb 08, 2023
Director, President and Chief Scientific
Director, President and Chief Scientific Form 4 Other acquisition or disposition -- -- 200,000
Feb 08, 2023
Director, President and Chief Scientific
Director, President and Chief Scientific Form 4 Other acquisition or disposition -- -- 250,000
Mar 23, 2023
Director, President and Chief Scientific
Director, President and Chief Scientific Form 4 Open market or private sale of non-derivative or derivative security 254 $800.59 200,250
Mar 23, 2023
Director, President and Chief Scientific
Director, President and Chief Scientific Form 4 Open market or private sale of non-derivative or derivative security 122 $801.16 200,128
Mar 23, 2023
Director, President and Chief Scientific
Director, President and Chief Scientific Form 4 Open market or private sale of non-derivative or derivative security 1,237 $802.54 198,891
Mar 23, 2023
Director, President and Chief Scientific
Director, President and Chief Scientific Form 4 Open market or private sale of non-derivative or derivative security 642 $803.30 198,249

* Represents the number of non-derivative securities directly held. (I) Indicates that some (or all) of these shares are held indirectly.