Date Name Title Filing Type Shares Traded Price Total Held
Aug 17, 2021
Director, President and Chief Scientific
Director, President and Chief Scientific Form 4 Other acquisition or disposition -- -- 5,848
Aug 17, 2021
Director, President and Chief Scientific
Director, President and Chief Scientific Form 4 Other acquisition or disposition -- -- 213,693
Aug 16, 2021
Director, President and Chief Scientific
Director, President and Chief Scientific Form 4 Open market or private sale of non-derivative or derivative security 46,925 $625.25 889,785
Aug 16, 2021
Director, President and Chief Scientific
Director, President and Chief Scientific Form 4 Open market or private sale of non-derivative or derivative security 2,302 $626.10 887,483
Aug 13, 2021
Director, President and Chief Scientific
Director, President and Chief Scientific Form 4 Open market or private sale of non-derivative or derivative security 773 $625.00 936,710
Aug 06, 2021
Director, President and Chief Scientific
Director, President and Chief Scientific Form 4 Other acquisition or disposition -- -- 5,848
Aug 05, 2021
Director, President and Chief Scientific
Director, President and Chief Scientific Form 4 Open market or private sale of non-derivative or derivative security 50,000 $600.06 937,483
Jun 24, 2021
Director, President and Chief Scientific
Director, President and Chief Scientific Form 4 Bona fide gift 211,585 -- 213,693
Jun 24, 2021
Director, President and Chief Scientific
Director, President and Chief Scientific Form 4 Bona fide gift 211,585 -- --
Jun 23, 2021
Director, President and Chief Scientific
Director, President and Chief Scientific Form 4 Other acquisition or disposition -- -- 987,483

* Represents the number of non-derivative securities directly held. (I) Indicates that some (or all) of these shares are held indirectly.