Date Name Title Type Shares Traded Price
Aug 09, 2022
Director
Director Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 15,000 $177.82
Aug 09, 2022
Director
Director Open market or private sale of non-derivative or derivative security 6,814 $620.47
Aug 09, 2022
Director
Director Open market or private sale of non-derivative or derivative security 8,186 $621.27
Aug 09, 2022
Director
Director Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 15,000 --
Aug 08, 2022
EVP Research and Development
EVP Research and Development Other acquisition or disposition -- --
Aug 08, 2022
EVP Research and Development
EVP Research and Development Other acquisition or disposition -- --
Aug 05, 2022
EVP Research and Development
EVP Research and Development Open market or private sale of non-derivative or derivative security 176 $606.78
Aug 05, 2022
EVP Research and Development
EVP Research and Development Open market or private sale of non-derivative or derivative security 724 $607.47
Aug 05, 2022
EVP Research and Development
EVP Research and Development Open market or private sale of non-derivative or derivative security 610 $608.70
Aug 05, 2022
EVP Research and Development
EVP Research and Development Open market or private sale of non-derivative or derivative security 3,044 $609.62

* Represents the number of non-derivative securities directly held. (I) Indicates that some (or all) of these shares are held indirectly.