Date Name Title Type Shares Traded Price
Aug 05, 2022
EVP Research and Development
EVP Research and Development Open market or private sale of non-derivative or derivative security 3,931 $610.49
Aug 05, 2022
EVP Research and Development
EVP Research and Development Open market or private sale of non-derivative or derivative security 2,022 $611.44
Aug 05, 2022
EVP Research and Development
EVP Research and Development Open market or private sale of non-derivative or derivative security 2,076 $612.43
Aug 05, 2022
EVP Research and Development
EVP Research and Development Open market or private sale of non-derivative or derivative security 3,218 $613.49
Aug 05, 2022
EVP Research and Development
EVP Research and Development Open market or private sale of non-derivative or derivative security 4,112 $614.35
Aug 05, 2022
EVP Research and Development
EVP Research and Development Open market or private sale of non-derivative or derivative security 1,610 $615.49
Aug 05, 2022
EVP Research and Development
EVP Research and Development Open market or private sale of non-derivative or derivative security 535 $616.40
Aug 05, 2022
EVP Research and Development
EVP Research and Development Open market or private sale of non-derivative or derivative security 424 $617.43
Aug 05, 2022
EVP Research and Development
EVP Research and Development Open market or private sale of non-derivative or derivative security 521 $618.27
Aug 05, 2022
EVP Research and Development
EVP Research and Development Open market or private sale of non-derivative or derivative security 502 $619.64

* Represents the number of non-derivative securities directly held. (I) Indicates that some (or all) of these shares are held indirectly.