Date Name Title Type Shares Traded Price
Aug 05, 2022
EVP Research and Development
EVP Research and Development Open market or private sale of non-derivative or derivative security 177 $620.11
Aug 05, 2022
EVP Research and Development
EVP Research and Development Open market or private sale of non-derivative or derivative security 100 $621.11
Aug 04, 2022
Director
Director Bona fide gift 2,500 --
Aug 04, 2022
Director
Director Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 3,613 $482.68
Aug 04, 2022
Director
Director Open market or private sale of non-derivative or derivative security 4,887 $620.85
Aug 04, 2022
Director
Director Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 4,361 $374.12
Aug 04, 2022
Director
Director Open market or private sale of non-derivative or derivative security 4,156 $621.54
Aug 04, 2022
Director
Director Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 2,479 $380.95
Aug 04, 2022
Director
Director Open market or private sale of non-derivative or derivative security 1,410 $622.06
Aug 04, 2022
Director
Director Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 4,361 --

* Represents the number of non-derivative securities directly held. (I) Indicates that some (or all) of these shares are held indirectly.