Date Name Title Type Shares Traded Price
Aug 04, 2022
Director
Director Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 2,479 --
Aug 04, 2022
Director
Director Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 3,613 --
Aug 04, 2022
EVP Research and Development
EVP Research and Development Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 95,000 $270.43
Aug 04, 2022
EVP Research and Development
EVP Research and Development Payment of exercise price or tax liability by delivering or withholding securities incident to the receipt, exercise or vesting of a security issued in accordance with Rule 16b-3 71,218 $613.00
Aug 04, 2022
EVP Research and Development
EVP Research and Development Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 95,000 --
Aug 02, 2022
EVP Commercial
EVP Commercial Other acquisition or disposition -- --
Aug 01, 2022
EVP Commercial
EVP Commercial Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 1,100 $342.93
Aug 01, 2022
EVP Commercial
EVP Commercial Open market or private sale of non-derivative or derivative security 1,100 $581.53
Aug 01, 2022
EVP Commercial
EVP Commercial Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 1,100 --
Jul 05, 2022
EVP Commercial
EVP Commercial Other acquisition or disposition -- --

* Represents the number of non-derivative securities directly held. (I) Indicates that some (or all) of these shares are held indirectly.