Date Name Title Filing Type Shares Traded Price Total Held
Feb 16, 2016
Ten Percent Owner
Ten Percent Owner Form 4 Open market or private purchase of non-derivative or derivative security 14,303 $390.47 23,217,941
Jun 06, 2013
Director
Director Form 4 Bona fide gift 14,444 -- 14,444
Mar 21, 2014
Ten Percent Owner
Ten Percent Owner Form 4 Open market or private purchase of non-derivative or derivative security 14,463 $315.07 18,208,671
Dec 20, 2007
Director, Chief Exec Officer & President, Ten Percent Owner
Director, Chief Exec Officer & President, Ten Percent Owner Form 4 Payment of exercise price or tax liability by delivering or withholding securities incident to the receipt, exercise or vesting of a security issued in accordance with Rule 16b-3 14,466 $22.28 79,451
Jul 10, 2008
Director
Director Form 4 Bona fide gift 14,493 -- 282,372
Dec 03, 2012
SVP Fin & Admin CFO Asst Secy
SVP Fin & Admin CFO Asst Secy Form 4 Bona fide gift 14,500 -- 69,227
Dec 03, 2012
SVP Fin & Admin CFO Asst Secy
SVP Fin & Admin CFO Asst Secy Form 4 Bona fide gift 14,500 -- 14,500
Jul 09, 2014
Ten Percent Owner
Ten Percent Owner Form 4 Open market or private purchase of non-derivative or derivative security 14,532 $307.22 21,462,959
Dec 18, 2009
SVP Clinical Development
SVP Clinical Development Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 14,543 -- 14,543
May 21, 2020
Director, Chairman of the Board
Director, Chairman of the Board Form 4 Open market or private sale of non-derivative or derivative security 14,548 $566.42 346,675

* Represents the number of non-derivative securities directly held. (I) Indicates that some (or all) of these shares are held indirectly.