Date Name Title Filing Type Shares Traded Price Total Held
Dec 29, 2006
Director, Chief Exec Officer & President, Ten Percent Owner
Director, Chief Exec Officer & President, Ten Percent Owner Form 5 Bona fide gift 500 -- 61,165
Dec 26, 2006
Director
Director Form 4 Bona fide gift 10,529 -- 349,113
Dec 20, 2006
Director
Director Form 4 Other acquisition or disposition -- -- 1,490
Dec 20, 2006
Director
Director Form 4 Other acquisition or disposition -- -- 219,801
Dec 20, 2006
Director
Director Form 4 Other acquisition or disposition -- -- 236,536
Dec 18, 2006
SVP Fin & Admin, CFO, & Treas
SVP Fin & Admin, CFO, & Treas Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 4,921 -- 4,921
Dec 18, 2006
SVP Fin & Admin, CFO, & Treas
SVP Fin & Admin, CFO, & Treas Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 70,079 -- 70,079
Dec 18, 2006
VP, Gen Counsel & Secretary
VP, Gen Counsel & Secretary Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 4,921 -- 4,921
Dec 18, 2006
VP, Gen Counsel & Secretary
VP, Gen Counsel & Secretary Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 35,079 -- 35,079
Dec 18, 2006
SVP, Clinical Development
SVP, Clinical Development Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 20,000 -- 20,000

* Represents the number of non-derivative securities directly held. (I) Indicates that some (or all) of these shares are held indirectly.