Date Name Title Filing Type Shares Traded Price Total Held
Nov 01, 2021
EVP Commercial
EVP Commercial Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 1,000 -- 11,000
Nov 03, 2021
EVP Commercial
EVP Commercial Form 4 Other acquisition or disposition -- -- 116
Dec 01, 2021
EVP Commercial
EVP Commercial Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 1,000 $342.93 18,038
Dec 01, 2021
EVP Commercial
EVP Commercial Form 4 Open market or private sale of non-derivative or derivative security 1,000 $639.13 17,038
Dec 01, 2021
EVP Commercial
EVP Commercial Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 1,000 -- 10,000
Dec 02, 2021
EVP Commercial
EVP Commercial Form 4 Other acquisition or disposition -- -- 116
Dec 08, 2021
EVP Research and Development
EVP Research and Development Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 2,926 -- 53,883
Dec 08, 2021
EVP Research and Development
EVP Research and Development Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 12,494 -- 12,494
Dec 08, 2021
Director
Director Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 1,861 -- 318,669
Dec 08, 2021
Director
Director Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 21,198 -- 21,198

* Represents the number of non-derivative securities directly held. (I) Indicates that some (or all) of these shares are held indirectly.