Date Name Title Filing Type Shares Traded Price Total Held
Mar 27, 2023
Director, President and Chief Scientific
Director, President and Chief Scientific Form 4 Other acquisition or disposition -- -- 250,000
Feb 08, 2023
Director, President and Chief Scientific
Director, President and Chief Scientific Form 4 Other acquisition or disposition -- -- 250,000
Dec 17, 2007
Director, Chief Exec Officer & President, Ten Percent Owner
Director, Chief Exec Officer & President, Ten Percent Owner Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 250,000 -- 250,000
Dec 18, 2006
Director, Chief Exec Officer & President, Ten Percent Owner
Director, Chief Exec Officer & President, Ten Percent Owner Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 250,000 -- 250,000
Dec 19, 2005
Director, Chief Exec Officer & President, Ten Percent Owner
Director, Chief Exec Officer & President, Ten Percent Owner Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 250,000 -- 250,000
Dec 15, 2003
Director, Chief Exec Officer & President
Director, Chief Exec Officer & President Form 4/A Grant, award or other acquisition pursuant to Rule 16b-3(d) 15,384 -- 250,000
Jun 13, 2019
Director, President and CSO
Director, President and CSO Form 4 Bona fide gift 500,000 -- 253,316
Sep 18, 2013
Director, President & CEO
Director, President & CEO Form 4 Payment of exercise price or tax liability by delivering or withholding securities incident to the receipt, exercise or vesting of a security issued in accordance with Rule 16b-3 6,808 $304.38 253,668
Aug 11, 2014
Director, Chairman of the Board
Director, Chairman of the Board Form 4 Open market or private sale of non-derivative or derivative security 300 $341.02 256,568
Aug 11, 2014
Director, Chairman of the Board
Director, Chairman of the Board Form 4 Open market or private sale of non-derivative or derivative security 9,072 $340.02 256,868

* Represents the number of non-derivative securities directly held. (I) Indicates that some (or all) of these shares are held indirectly.