Date Name Title Filing Type Shares Traded Price Total Held
Dec 13, 2018
Director, President and Chief Scientific
Director, President and Chief Scientific Form 4 Bona fide gift 118,993 -- --
Dec 13, 2018
Director, President and Chief Scientific
Director, President and Chief Scientific Form 4 Bona fide gift 118,993 -- 602,594
Nov 16, 2018
Director, Chairman of the Board
Director, Chairman of the Board Form 4 Bona fide gift 16,161 -- 314,877
Nov 16, 2018
Director, President and CSO
Director, President and CSO Form 4 Bona fide gift 1,176 -- 483,601
Nov 15, 2018
Director, Chairman of the Board
Director, Chairman of the Board Form 4 Bona fide gift 19,202 -- 331,038
Nov 13, 2018
Director, Chairman of the Board
Director, Chairman of the Board Form 4 Bona fide gift 37,209 -- 350,240
Nov 01, 2018
Director, President and CSO
Director, President and CSO Form 4 Bona fide gift 24,643 -- --
Oct 25, 2018
VP Controller
VP Controller Form 4 Bona fide gift 2,950 -- 1,397
Oct 25, 2018
VP Controller
VP Controller Form 4 Bona fide gift 2,950 -- 2,950
Oct 04, 2018
Director, Chairman of the Board
Director, Chairman of the Board Form 4 Bona fide gift 521 -- 147,413

* Represents the number of non-derivative securities directly held. (I) Indicates that some (or all) of these shares are held indirectly.