Date Name Title Filing Type Shares Traded Price Total Held
Aug 21, 2023
EVP Research and Development
EVP Research and Development Form 4 Payment of exercise price or tax liability by delivering or withholding securities incident to the receipt, exercise or vesting of a security issued in accordance with Rule 16b-3 38,335 $833.39 64,765
Mar 27, 2023
EVP Finance CFO
EVP Finance CFO Form 4 Payment of exercise price or tax liability by delivering or withholding securities incident to the receipt, exercise or vesting of a security issued in accordance with Rule 16b-3 589 $825.17 32,316
Mar 27, 2023
EVP Finance CFO
EVP Finance CFO Form 4 Payment of exercise price or tax liability by delivering or withholding securities incident to the receipt, exercise or vesting of a security issued in accordance with Rule 16b-3 2,204 $825.17 33,112
Mar 23, 2023
EVP General Counsel and Secret
EVP General Counsel and Secret Form 4 Payment of exercise price or tax liability by delivering or withholding securities incident to the receipt, exercise or vesting of a security issued in accordance with Rule 16b-3 6,742 $801.59 27,471
Feb 22, 2023
Director
Director Form 4 Payment of exercise price or tax liability by delivering or withholding securities incident to the receipt, exercise or vesting of a security issued in accordance with Rule 16b-3 29,005 $750.16 337,578
Feb 12, 2023
EVP Commercial
EVP Commercial Form 4 Payment of exercise price or tax liability by delivering or withholding securities incident to the receipt, exercise or vesting of a security issued in accordance with Rule 16b-3 1,276 $751.78 20,803
Feb 03, 2023
SVP Controller
SVP Controller Form 4 Payment of exercise price or tax liability by delivering or withholding securities incident to the receipt, exercise or vesting of a security issued in accordance with Rule 16b-3 3,286 $774.29 20,295
Feb 03, 2023
EVP Finance CFO
EVP Finance CFO Form 4 Payment of exercise price or tax liability by delivering or withholding securities incident to the receipt, exercise or vesting of a security issued in accordance with Rule 16b-3 2,248 $774.29 32,857
Dec 09, 2022
SVP Controller
SVP Controller Form 4 Payment of exercise price or tax liability by delivering or withholding securities incident to the receipt, exercise or vesting of a security issued in accordance with Rule 16b-3 247 $753.28 16,655
Dec 09, 2022
EVP Finance CFO
EVP Finance CFO Form 4 Payment of exercise price or tax liability by delivering or withholding securities incident to the receipt, exercise or vesting of a security issued in accordance with Rule 16b-3 492 $753.28 28,991

* Represents the number of non-derivative securities directly held. (I) Indicates that some (or all) of these shares are held indirectly.