001000 - Statement - BALANCE SHEETS link:presentationLink link:calculationLink link:definitionLink 002000 - Statement - STATEMENTS OF OPERATIONS link:presentationLink link:calculationLink link:definitionLink 003000 - Statement - STATEMENTS OF STOCKHOLDERS' EQUITY link:presentationLink link:calculationLink link:definitionLink 004000 - Statement - STATEMENTS OF CASH FLOWS link:presentationLink link:calculationLink link:definitionLink 001010 - Statement - BALANCE SHEETS (Parenthetical) link:presentationLink link:calculationLink link:definitionLink 021010 - Disclosure - Interim Financial Statements link:presentationLink link:calculationLink link:definitionLink 006180 - Disclosure - Net Loss Per Share Data link:presentationLink link:calculationLink link:definitionLink 006190 - Disclosure - Statement of Cash Flows link:presentationLink link:calculationLink link:definitionLink 006060 - Disclosure - Marketable Securities link:presentationLink link:calculationLink link:definitionLink 006080 - Disclosure - Accounts Payable and Accrued Expenses link:presentationLink link:calculationLink link:definitionLink 021020 - Disclosure - Comprehensive Loss link:presentationLink link:calculationLink link:definitionLink 021030 - Disclosure - Lease - Tarrytown, New York Facilities link:presentationLink link:calculationLink link:definitionLink 021040 - Disclosure - Future Impact of Recently Issued Accounting Standards link:presentationLink link:calculationLink link:definitionLink 006200 - Disclosure - Subsequent Events link:presentationLink link:calculationLink link:definitionLink 021050 - Disclosure - Revisions of Previously Issued Financial Statements link:presentationLink link:calculationLink link:definitionLink 021060 - Disclosure - Test link:presentationLink link:calculationLink link:definitionLink 003010 - Statement - STATEMENTS OF STOCKHOLDERS' EQUITY (Parenthetical) link:presentationLink link:calculationLink link:definitionLink 021070 - Disclosure - Extension of Technology Licensing Agreement with Astellas link:presentationLink link:calculationLink link:definitionLink 021080 - Disclosure - Extension of Licensing Agreement with Astellas link:presentationLink link:calculationLink link:definitionLink 006050 - Disclosure - ARCALYST (rilonacept) Product Revenue link:presentationLink link:calculationLink link:definitionLink 006020 - Disclosure - Summary of Significant Accounting Policies link:presentationLink link:calculationLink link:definitionLink 006010 - Disclosure - Organization and Business link:presentationLink link:calculationLink link:definitionLink 006030 - Disclosure - Collaboration and Contract Research Agreement link:presentationLink link:calculationLink link:definitionLink 006040 - Disclosure - Technology Licensing Agreement link:presentationLink link:calculationLink link:definitionLink 006070 - Disclosure - Property Plant and Equipment link:presentationLink link:calculationLink link:definitionLink 006090 - Disclosure - Deferred Revenue link:presentationLink link:calculationLink link:definitionLink 006100 - Disclosure - Convertible Debt link:presentationLink link:calculationLink link:definitionLink 006110 - Disclosure - Commitments and Contingencies link:presentationLink link:calculationLink link:definitionLink 006120 - Disclosure - Stockholders' Equity link:presentationLink link:calculationLink link:definitionLink 006150 - Disclosure - Employee Savings Plan link:presentationLink link:calculationLink link:definitionLink 006160 - Disclosure - Income Taxes link:presentationLink link:calculationLink link:definitionLink 006210 - Disclosure - Unaudited Quarterly Result link:presentationLink link:calculationLink link:definitionLink 006130 - Disclosure - long-Term Incentive Plans link:presentationLink link:calculationLink link:definitionLink 006140 - Disclosure - Executive Stock Purchase Plan link:presentationLink link:calculationLink link:definitionLink 006170 - Disclosure - Legal Matters link:presentationLink link:calculationLink link:definitionLink