Date Name Title Filing Type Shares Traded Price Total Held
May 05, 2004
VP Clinical Programs
VP Clinical Programs Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 20,000 $7.44 32,530
May 05, 2004
VP Clinical Programs
VP Clinical Programs Form 4 Open market or private sale of non-derivative or derivative security 20,000 $13.50 12,530
May 05, 2004
VP Clinical Programs
VP Clinical Programs Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 20,000 -- 15,000
Dec 15, 2003
VP, Clinical Sciences
VP, Clinical Sciences Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 15,000 -- 15,000
Oct 08, 2004
VP Clinical Programs
VP Clinical Programs Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 8,000 $7.44 18,530
Oct 08, 2004
VP Clinical Programs
VP Clinical Programs Form 4 Open market or private sale of non-derivative or derivative security 8,000 $7.95 10,530
Oct 08, 2004
VP Clinical Programs
VP Clinical Programs Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 8,000 -- 500
Oct 08, 2004
VP Clinical Programs
VP Clinical Programs Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 5,000 $7.41 15,530
Oct 08, 2004
VP Clinical Programs
VP Clinical Programs Form 4 Open market or private sale of non-derivative or derivative security 5,000 $7.93 10,530
Oct 08, 2004
VP Clinical Programs
VP Clinical Programs Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 5,000 -- 6,874

* Represents the number of non-derivative securities directly held. (I) Indicates that some (or all) of these shares are held indirectly.