Date Name Title Filing Type Shares Traded Price Total Held
Sep 07, 2011
VP Regulatory Development and
VP Regulatory Development and Form 4 Open market or private sale of non-derivative or derivative security 400 $67.48 73,059
Nov 30, 2012
VP Regulat Dev & Med Safety
VP Regulat Dev & Med Safety Form 4 Open market or private sale of non-derivative or derivative security 430 $178.27 10,846
Feb 04, 2010
VP Regul Devel & Med Safety
VP Regul Devel & Med Safety Form 4 Open market or private sale of non-derivative or derivative security 471 $27.48 66,956
Nov 30, 2012
VP Regulat Dev & Med Safety
VP Regulat Dev & Med Safety Form 4 Open market or private sale of non-derivative or derivative security 521 $182.44 1,200
Aug 12, 2009
VP Regul Devel & Clin Safety
VP Regul Devel & Clin Safety Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 529 $8.50 67,485
Aug 12, 2009
VP Regul Devel & Clin Safety
VP Regul Devel & Clin Safety Form 4 Open market or private sale of non-derivative or derivative security 529 $22.99 66,956
Aug 12, 2009
VP Regul Devel & Clin Safety
VP Regul Devel & Clin Safety Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 529 -- 4,550
Jan 05, 2005
VP, Regulatory Development
VP, Regulatory Development Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 529 -- 5,079
Feb 03, 2010
VP Regul Devel & Med Safety
VP Regul Devel & Med Safety Form 4 Payment of exercise price or tax liability by delivering or withholding securities incident to the receipt, exercise or vesting of a security issued in accordance with Rule 16b-3 695 $28.02 70,090
Jan 19, 2011
VP Regul Devel & Med Safety
VP Regul Devel & Med Safety Form 4 Open market or private sale of non-derivative or derivative security 699 $35.42 69,649

* Represents the number of non-derivative securities directly held. (I) Indicates that some (or all) of these shares are held indirectly.