Date Name Title Filing Type Shares Traded Price Total Held
Sep 01, 2009
VP Regul Devel & Med Safety
VP Regul Devel & Med Safety Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 10,000 -- --
Jan 05, 2005
VP, Regulatory Development
VP, Regulatory Development Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 10,000 -- 10,000
Dec 28, 2009
VP Regul Devel & Med Safety
VP Regul Devel & Med Safety Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 9,927 $8.50 76,883
Dec 28, 2009
VP Regul Devel & Med Safety
VP Regul Devel & Med Safety Form 4 Open market or private sale of non-derivative or derivative security 9,927 $23.99 66,956
Dec 28, 2009
VP Regul Devel & Med Safety
VP Regul Devel & Med Safety Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 9,927 -- --
Sep 22, 2008
VP, Regul Devel & Med Safety
VP, Regul Devel & Med Safety Form 4 Open market or private sale of non-derivative or derivative security 9,692 $22.84 69,356
Jan 18, 2011
VP Regul Devel & Med Safety
VP Regul Devel & Med Safety Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 8,812 $9.49 75,768
Jan 18, 2011
VP Regul Devel & Med Safety
VP Regul Devel & Med Safety Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 8,812 -- --
Sep 06, 2011
VP Regulatory Development and
VP Regulatory Development and Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 8,578 $11.64 82,037
Sep 06, 2011
VP Regulatory Development and
VP Regulatory Development and Form 4 Open market or private sale of non-derivative or derivative security 8,578 $66.42 73,459

* Represents the number of non-derivative securities directly held. (I) Indicates that some (or all) of these shares are held indirectly.