Date Name Title Filing Type Shares Traded Price Total Held
Aug 27, 2012
VP Regulatory Development and
VP Regulatory Development and Form 4 Other acquisition or disposition -- -- 1,200
Aug 27, 2012
VP Regulatory Development and
VP Regulatory Development and Form 4 Other acquisition or disposition -- -- 4,331
Aug 27, 2012
VP Regulatory Development and
VP Regulatory Development and Form 4 Other acquisition or disposition -- -- 1,200
Sep 04, 2012
VP Regulat Dev & Med Safety
VP Regulat Dev & Med Safety Form 4 Bona fide gift 19,947 -- 19,947
Nov 05, 2012
VP Regulat Dev & Med Safety
VP Regulat Dev & Med Safety Form 4 Bona fide gift 26,000 -- 16,644
Nov 05, 2012
VP Regulat Dev & Med Safety
VP Regulat Dev & Med Safety Form 4 Bona fide gift 26,000 -- 45,947
Nov 27, 2012
VP Regulat Dev & Med Safety
VP Regulat Dev & Med Safety Form 4 Bona fide gift 11,500 -- 11,500
Nov 27, 2012
VP Regulat Dev & Med Safety
VP Regulat Dev & Med Safety Form 4 Bona fide gift 11,500 -- 17,447
Nov 30, 2012
VP Regulat Dev & Med Safety
VP Regulat Dev & Med Safety Form 4 Open market or private sale of non-derivative or derivative security 224 $177.43 11,276
Nov 30, 2012
VP Regulat Dev & Med Safety
VP Regulat Dev & Med Safety Form 4 Open market or private sale of non-derivative or derivative security 430 $178.27 10,846

* Represents the number of non-derivative securities directly held. (I) Indicates that some (or all) of these shares are held indirectly.