Date Name Title Filing Type Shares Traded Price Total Held
Jan 05, 2005
VP, Regulatory Development
VP, Regulatory Development Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 13,235 -- 13,235
Dec 19, 2005
VP, Regulatory Development
VP, Regulatory Development Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 13,537 -- 13,537
Jan 05, 2005
VP, Regulatory Development
VP, Regulatory Development Form 4 Disposition to the issuer of issuer equity securities pursuant to Rule 16b-3(e) 13,650 -- --
Sep 18, 2013
VP Reg Dev & Med Safety
VP Reg Dev & Med Safety Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 15,000 $16.80 35,644
Sep 18, 2013
VP Reg Dev & Med Safety
VP Reg Dev & Med Safety Form 4 Open market or private sale of non-derivative or derivative security 15,000 $304.00 20,644
Sep 18, 2013
VP Reg Dev & Med Safety
VP Reg Dev & Med Safety Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 15,000 -- 9,048
Aug 23, 2012
VP Regulatory Development and
VP Regulatory Development and Form 4 Open market or private sale of non-derivative or derivative security 15,000 $144.00 46,144
Dec 15, 2003
VP, Regulatory Development
VP, Regulatory Development Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 15,000 -- 15,000
Apr 27, 2009
VP Regul Devel & Clin Safety
VP Regul Devel & Clin Safety Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 15,160 $6.50 82,116
Apr 27, 2009
VP Regul Devel & Clin Safety
VP Regul Devel & Clin Safety Form 4 Open market or private sale of non-derivative or derivative security 15,160 $12.74 66,956

* Represents the number of non-derivative securities directly held. (I) Indicates that some (or all) of these shares are held indirectly.