Date Name Title Filing Type Shares Traded Price Total Held
Aug 22, 2008
VP, Regul Devel & Med Safety
VP, Regul Devel & Med Safety Form 4 Bona fide gift 24,102 -- 69,356
Aug 22, 2008
VP, Regul Devel & Med Safety
VP, Regul Devel & Med Safety Form 4 Bona fide gift 24,102 -- --
Sep 16, 2008
VP, Regul Devel & Med Safety
VP, Regul Devel & Med Safety Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 25,000 $8.77 94,356
Sep 16, 2008
VP, Regul Devel & Med Safety
VP, Regul Devel & Med Safety Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 25,000 -- --
Jan 10, 2012
VP Regulatory Development and
VP Regulatory Development and Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 25,034 $20.32 97,182
Jan 10, 2012
VP Regulatory Development and
VP Regulatory Development and Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 25,034 -- --
Dec 18, 2006
VP, Regulatory Development
VP, Regulatory Development Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 25,034 -- 25,034
Jan 10, 2012
VP Regulatory Development and
VP Regulatory Development and Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 25,438 $21.92 86,582
Jan 10, 2012
VP Regulatory Development and
VP Regulatory Development and Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 25,438 -- --
Dec 17, 2007
VP, Regul Devel & Clin Safety
VP, Regul Devel & Clin Safety Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 25,438 -- 25,438

* Represents the number of non-derivative securities directly held. (I) Indicates that some (or all) of these shares are held indirectly.