Date Name Title Filing Type Shares Traded Price Total Held
May 10, 2013
SVP Research and Development S
SVP Research and Development S Form 4 Payment of exercise price or tax liability by delivering or withholding securities incident to the receipt, exercise or vesting of a security issued in accordance with Rule 16b-3 27,873 $268.40 72,026
May 14, 2021
EVP Research and Development
EVP Research and Development Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 40,000 -- 72,500
Jun 19, 2012
SVP Res & Dev Sciences
SVP Res & Dev Sciences Form 4 Open market or private sale of non-derivative or derivative security 24,848 $115.60 73,184
Apr 05, 2011
SVP Res and Dev Sciences
SVP Res and Dev Sciences Form 4 Open market or private sale of non-derivative or derivative security 11,200 $45.83 73,265
Nov 21, 2012
SVP Res and Devel Sciences
SVP Res and Devel Sciences Form 4 Open market or private sale of non-derivative or derivative security 9,200 $173.80 74,278
Nov 20, 2012
SVP Res and Devel Sciences
SVP Res and Devel Sciences Form 4 Payment of exercise price or tax liability by delivering or withholding securities incident to the receipt, exercise or vesting of a security issued in accordance with Rule 16b-3 1,708 $167.17 74,413
Aug 29, 2012
SVP Research and Development S
SVP Research and Development S Form 4 Open market or private sale of non-derivative or derivative security 1,500 $144.92 74,505
Aug 05, 2022
EVP Research and Development
EVP Research and Development Form 4 Open market or private sale of non-derivative or derivative security 610 $608.70 75,067
Sep 07, 2011
SVP Research and Development S
SVP Research and Development S Form 4 Open market or private sale of non-derivative or derivative security 7,373 $68.77 75,537
Aug 05, 2022
EVP Research and Development
EVP Research and Development Form 4 Open market or private sale of non-derivative or derivative security 724 $607.47 75,677

* Represents the number of non-derivative securities directly held. (I) Indicates that some (or all) of these shares are held indirectly.