Date Name Title Filing Type Shares Traded Price Total Held
Dec 15, 2004
SVP, PreclinDevel & Biomol Sci
SVP, PreclinDevel & Biomol Sci Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 89,463 -- 89,463
Jul 24, 2009
SVP Res and Dev Sciences
SVP Res and Dev Sciences Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 89,463 $9.49 89,813
Feb 13, 2012
SVP Research and Development S
SVP Research and Development S Form 4 Payment of exercise price or tax liability by delivering or withholding securities incident to the receipt, exercise or vesting of a security issued in accordance with Rule 16b-3 1,597 $113.35 90,323
Feb 13, 2012
SVP Research and Development S
SVP Research and Development S Form 4 Payment of exercise price or tax liability by delivering or withholding securities incident to the receipt, exercise or vesting of a security issued in accordance with Rule 16b-3 257 $113.35 91,920
Feb 13, 2012
SVP Research and Development S
SVP Research and Development S Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 3,432 $8.50 92,177
Dec 15, 2003
SVP, PreclinDevel & Biomol Sci
SVP, PreclinDevel & Biomol Sci Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 92,308 -- 92,308
Nov 05, 2015
EVP Research and Development
EVP Research and Development Form 4 Payment of exercise price or tax liability by delivering or withholding securities incident to the receipt, exercise or vesting of a security issued in accordance with Rule 16b-3 4,047 $567.63 92,982
Aug 28, 2012
SVP Research and Development S
SVP Research and Development S Form 4 Payment of exercise price or tax liability by delivering or withholding securities incident to the receipt, exercise or vesting of a security issued in accordance with Rule 16b-3 6,017 $145.70 93,104
Dec 13, 2013
SVP Research and Development S
SVP Research and Development S Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 95,000 -- 95,000
Dec 18, 2006
SVP, Therap & Clin Prog Dev
SVP, Therap & Clin Prog Dev Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 95,079 -- 95,079

* Represents the number of non-derivative securities directly held. (I) Indicates that some (or all) of these shares are held indirectly.