Date Name Title Filing Type Shares Traded Price Total Held
May 14, 2021
EVP Research and Development
EVP Research and Development Form 4 Payment of exercise price or tax liability by delivering or withholding securities incident to the receipt, exercise or vesting of a security issued in accordance with Rule 16b-3 7,204 $516.69 41,801
Apr 13, 2020
EVP Research and Development
EVP Research and Development Form 4 Payment of exercise price or tax liability by delivering or withholding securities incident to the receipt, exercise or vesting of a security issued in accordance with Rule 16b-3 7,582 $511.56 16,877
Jun 21, 2017
EVP Research and Development
EVP Research and Development Form 4 Payment of exercise price or tax liability by delivering or withholding securities incident to the receipt, exercise or vesting of a security issued in accordance with Rule 16b-3 1,201 $510.02 42,749
Jun 21, 2017
EVP Research and Development
EVP Research and Development Form 4 Payment of exercise price or tax liability by delivering or withholding securities incident to the receipt, exercise or vesting of a security issued in accordance with Rule 16b-3 10,493 $510.02 32,256
Jun 02, 2017
EVP Research and Development
EVP Research and Development Form 4 Open market or private sale of non-derivative or derivative security 200 $483.42 23,950
Jun 02, 2017
EVP Research and Development
EVP Research and Development Form 4 Open market or private sale of non-derivative or derivative security 808 $482.56 24,150
Jun 02, 2017
EVP Research and Development
EVP Research and Development Form 4 Open market or private sale of non-derivative or derivative security 695 $481.64 24,958
Jun 02, 2017
EVP Research and Development
EVP Research and Development Form 4 Open market or private sale of non-derivative or derivative security 309 $480.71 25,653
Jun 02, 2017
EVP Research and Development
EVP Research and Development Form 4 Open market or private sale of non-derivative or derivative security 100 $479.00 25,962
Jun 02, 2017
EVP Research and Development
EVP Research and Development Form 4 Open market or private sale of non-derivative or derivative security 100 $476.52 26,062

* Represents the number of non-derivative securities directly held. (I) Indicates that some (or all) of these shares are held indirectly.