Date Name Title Filing Type Shares Traded Price Total Held
Aug 21, 2023
EVP Research and Development
EVP Research and Development Form 4 Payment of exercise price or tax liability by delivering or withholding securities incident to the receipt, exercise or vesting of a security issued in accordance with Rule 16b-3 38,335 $833.39 64,765
Feb 12, 2014
SVP Research and Development S
SVP Research and Development S Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 40,000 $21.25 64,391
May 14, 2021
EVP Research and Development
EVP Research and Development Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 40,000 $179.13 64,280
Nov 05, 2015
EVP Research and Development
EVP Research and Development Form 4 Payment of exercise price or tax liability by delivering or withholding securities incident to the receipt, exercise or vesting of a security issued in accordance with Rule 16b-3 13,312 $567.63 64,130
Jun 19, 2012
SVP Res & Dev Sciences
SVP Res & Dev Sciences Form 4 Open market or private sale of non-derivative or derivative security 9,080 $116.41 64,104
Aug 05, 2022
EVP Research and Development
EVP Research and Development Form 4 Open market or private sale of non-derivative or derivative security 2,076 $612.43 63,994
Feb 12, 2020
EVP Research and Development
EVP Research and Development Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 25,000 -- 63,079
Feb 12, 2014
SVP Research and Development S
SVP Research and Development S Form 4 Payment of exercise price or tax liability by delivering or withholding securities incident to the receipt, exercise or vesting of a security issued in accordance with Rule 16b-3 2,619 $324.44 61,772
Feb 15, 2012
SVP Research and Development S
SVP Research and Development S Form 4 Open market or private sale of non-derivative or derivative security 19,057 $107.79 61,146
Nov 21, 2012
SVP Res and Devel Sciences
SVP Res and Devel Sciences Form 4 Open market or private sale of non-derivative or derivative security 13,157 $174.47 61,121

* Represents the number of non-derivative securities directly held. (I) Indicates that some (or all) of these shares are held indirectly.