Date Name Title Filing Type Shares Traded Price Total Held
Nov 06, 2015
EVP Research and Development
EVP Research and Development Form 4 Open market or private sale of non-derivative or derivative security 9,555 $562.37 54,575
Aug 05, 2022
EVP Research and Development
EVP Research and Development Form 4 Open market or private sale of non-derivative or derivative security 1,610 $615.49 55,054
Aug 28, 2012
SVP Research and Development S
SVP Research and Development S Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 40,000 -- 55,438
Aug 05, 2022
EVP Research and Development
EVP Research and Development Form 4 Open market or private sale of non-derivative or derivative security 4,112 $614.35 56,664
Feb 07, 2024
EVP Research and Development
EVP Research and Development Form 4 Open market or private sale of non-derivative or derivative security 601 $949.45 57,461
Mar 30, 2011
SVP Res and Dev Sciences
SVP Res and Dev Sciences Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 7,692 $13.00 58,042
Feb 07, 2024
EVP Research and Development
EVP Research and Development Form 4 Open market or private sale of non-derivative or derivative security 1,894 $948.69 58,062
Dec 16, 2016
EVP Research and Development
EVP Research and Development Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 58,342 -- 58,342
Aug 22, 2023
EVP Research and Development
EVP Research and Development Form 4 Open market or private sale of non-derivative or derivative security 6,309 $840.53 58,456
May 13, 2013
SVP Research and Development S
SVP Research and Development S Form 4 Open market or private sale of non-derivative or derivative security 13,378 $276.71 58,648

* Represents the number of non-derivative securities directly held. (I) Indicates that some (or all) of these shares are held indirectly.