Date Name Title Filing Type Shares Traded Price Total Held
Aug 29, 2012
SVP Research and Development S
SVP Research and Development S Form 4 Open market or private sale of non-derivative or derivative security 9,386 $145.44 65,119
Aug 05, 2022
EVP Research and Development
EVP Research and Development Form 4 Open market or private sale of non-derivative or derivative security 2,022 $611.44 66,070
Jan 05, 2005
SVP, PreclinDevel & Biomol Sci
SVP, PreclinDevel & Biomol Sci Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 63,234 -- 66,666
Nov 20, 2012
SVP Res and Devel Sciences
SVP Res and Devel Sciences Form 4 Payment of exercise price or tax liability by delivering or withholding securities incident to the receipt, exercise or vesting of a security issued in accordance with Rule 16b-3 7,694 $167.17 66,719
Sep 07, 2011
SVP Research and Development S
SVP Research and Development S Form 4 Open market or private sale of non-derivative or derivative security 8,286 $69.58 67,251
Nov 14, 2011
SVP Research and Development S
SVP Research and Development S Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 17,182 $11.64 67,532
Aug 05, 2022
EVP Research and Development
EVP Research and Development Form 4 Open market or private sale of non-derivative or derivative security 3,931 $610.49 68,092
Dec 16, 2015
EVP Research and Development
EVP Research and Development Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 68,638 -- 68,638
Feb 14, 2012
SVP Research and Development S
SVP Research and Development S Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 50,000 -- 69,048
Aug 05, 2022
EVP Research and Development
EVP Research and Development Form 4 Open market or private sale of non-derivative or derivative security 3,044 $609.62 72,023

* Represents the number of non-derivative securities directly held. (I) Indicates that some (or all) of these shares are held indirectly.