Date Name Title Filing Type Shares Traded Price Total Held
Dec 17, 2007
SVP, Research & Devel Sciences
SVP, Research & Devel Sciences Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 95,438 -- 95,438
Nov 05, 2015
EVP Research and Development
EVP Research and Development Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 75,000 $30.63 97,029
Jun 18, 2012
SVP Res & Dev Sciences
SVP Res & Dev Sciences Form 4 Payment of exercise price or tax liability by delivering or withholding securities incident to the receipt, exercise or vesting of a security issued in accordance with Rule 16b-3 39,411 $115.29 98,032
May 13, 2019
EVP Research and Development
EVP Research and Development Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 25,000 -- 98,079
Aug 28, 2012
SVP Research and Development S
SVP Research and Development S Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 40,000 $21.92 99,121
May 10, 2013
SVP Research and Development S
SVP Research and Development S Form 4 Payment of exercise price or tax liability by delivering or withholding securities incident to the receipt, exercise or vesting of a security issued in accordance with Rule 16b-3 4,527 $268.40 99,899
Feb 14, 2012
SVP Research and Development S
SVP Research and Development S Form 4 Open market or private sale of non-derivative or derivative security 8,510 $109.61 100,212
Nov 20, 2012
SVP Res and Devel Sciences
SVP Res and Devel Sciences Form 4 Payment of exercise price or tax liability by delivering or withholding securities incident to the receipt, exercise or vesting of a security issued in accordance with Rule 16b-3 3,768 $167.17 100,451
Aug 21, 2023
EVP Research and Development
EVP Research and Development Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 50,000 $399.66 103,100
Nov 20, 2012
SVP Res and Devel Sciences
SVP Res and Devel Sciences Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 37,500 $16.80 104,219

* Represents the number of non-derivative securities directly held. (I) Indicates that some (or all) of these shares are held indirectly.