Date Name Title Filing Type Shares Traded Price Total Held
Feb 26, 2020
EVP Research and Development
EVP Research and Development Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 25,000 $52.03 36,380
Feb 26, 2020
EVP Research and Development
EVP Research and Development Form 4 Payment of exercise price or tax liability by delivering or withholding securities incident to the receipt, exercise or vesting of a security issued in accordance with Rule 16b-3 14,651 $451.89 21,729
Feb 14, 2020
EVP Research and Development
EVP Research and Development Form 4 Other acquisition or disposition -- -- 5,736
Feb 14, 2020
EVP Research and Development
EVP Research and Development Form 4 Other acquisition or disposition -- -- 7,831
Feb 14, 2020
EVP Research and Development
EVP Research and Development Form 4 Other acquisition or disposition -- -- 13,700
Feb 13, 2020
EVP Research and Development
EVP Research and Development Form 4 Open market or private sale of non-derivative or derivative security 4,302 $399.80 17,356
Feb 13, 2020
EVP Research and Development
EVP Research and Development Form 4 Open market or private sale of non-derivative or derivative security 2,608 $400.54 14,748
Feb 13, 2020
EVP Research and Development
EVP Research and Development Form 4 Open market or private sale of non-derivative or derivative security 2,058 $401.46 12,690
Feb 13, 2020
EVP Research and Development
EVP Research and Development Form 4 Open market or private sale of non-derivative or derivative security 1,279 $402.35 11,411
Feb 13, 2020
EVP Research and Development
EVP Research and Development Form 4 Open market or private sale of non-derivative or derivative security 31 $406.44 11,380

* Represents the number of non-derivative securities directly held. (I) Indicates that some (or all) of these shares are held indirectly.