Date Name Title Filing Type Shares Traded Price Total Held
Feb 12, 2020
EVP Research and Development
EVP Research and Development Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 25,000 $52.03 36,380
Feb 12, 2020
EVP Research and Development
EVP Research and Development Form 4 Payment of exercise price or tax liability by delivering or withholding securities incident to the receipt, exercise or vesting of a security issued in accordance with Rule 16b-3 14,722 $402.34 21,658
Feb 12, 2020
EVP Research and Development
EVP Research and Development Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 25,000 -- 63,079
Dec 13, 2019
EVP Research and Development
EVP Research and Development Form 4 Other acquisition or disposition -- -- 5,736
Dec 13, 2019
EVP Research and Development
EVP Research and Development Form 4 Other acquisition or disposition -- -- 7,831
Dec 13, 2019
EVP Research and Development
EVP Research and Development Form 4 Other acquisition or disposition -- -- 13,700
Dec 11, 2019
EVP Research and Development
EVP Research and Development Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 2,625 -- 11,380
Dec 11, 2019
EVP Research and Development
EVP Research and Development Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 24,500 -- 24,500
Nov 26, 2019
EVP Research and Development
EVP Research and Development Form 4 Open market or private sale of non-derivative or derivative security 1,422 $363.58 25,039
Nov 26, 2019
EVP Research and Development
EVP Research and Development Form 4 Open market or private sale of non-derivative or derivative security 2,284 $364.20 22,755

* Represents the number of non-derivative securities directly held. (I) Indicates that some (or all) of these shares are held indirectly.