Date Name Title Filing Type Shares Traded Price Total Held
Jun 14, 2017
EVP Research and Development
EVP Research and Development Form 4 Payment of exercise price or tax liability by delivering or withholding securities incident to the receipt, exercise or vesting of a security issued in accordance with Rule 16b-3 906 $475.56 43,339
Jun 14, 2017
EVP Research and Development
EVP Research and Development Form 4 Payment of exercise price or tax liability by delivering or withholding securities incident to the receipt, exercise or vesting of a security issued in accordance with Rule 16b-3 10,822 $475.56 32,517
Jun 02, 2017
EVP Research and Development
EVP Research and Development Form 4 Open market or private sale of non-derivative or derivative security 100 $475.33 26,162
Jun 02, 2017
EVP Research and Development
EVP Research and Development Form 4 Open market or private sale of non-derivative or derivative security 100 $474.82 26,262
Jun 15, 2017
EVP Research and Development
EVP Research and Development Form 4 Open market or private sale of non-derivative or derivative security 100 $474.48 23,950
Jun 15, 2017
EVP Research and Development
EVP Research and Development Form 4 Open market or private sale of non-derivative or derivative security 100 $472.95 24,050
Jun 02, 2017
EVP Research and Development
EVP Research and Development Form 4 Open market or private sale of non-derivative or derivative security 100 $472.10 26,362
Jun 15, 2017
EVP Research and Development
EVP Research and Development Form 4 Open market or private sale of non-derivative or derivative security 100 $471.15 24,150
Jun 15, 2017
EVP Research and Development
EVP Research and Development Form 4 Open market or private sale of non-derivative or derivative security 2,426 $470.57 24,250
Jun 02, 2017
EVP Research and Development
EVP Research and Development Form 4 Open market or private sale of non-derivative or derivative security 100 $470.49 26,462

* Represents the number of non-derivative securities directly held. (I) Indicates that some (or all) of these shares are held indirectly.