Date Name Title Filing Type Shares Traded Price Total Held
Jan 05, 2005
SVP, PreclinDevel & Biomol Sci
SVP, PreclinDevel & Biomol Sci Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 63,234 -- 66,666
Dec 16, 2016
EVP Research and Development
EVP Research and Development Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 58,342 -- 58,342
May 10, 2013
SVP Research and Development S
SVP Research and Development S Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 55,438 $21.92 104,426
May 10, 2013
SVP Research and Development S
SVP Research and Development S Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 55,438 -- --
Aug 21, 2023
EVP Research and Development
EVP Research and Development Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 50,000 $399.66 103,100
Aug 21, 2023
EVP Research and Development
EVP Research and Development Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 50,000 -- 30,750
Dec 12, 2017
EVP Research and Development
EVP Research and Development Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 50,000 -- 50,000
Feb 14, 2012
SVP Research and Development S
SVP Research and Development S Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 50,000 $16.80 140,323
Feb 14, 2012
SVP Research and Development S
SVP Research and Development S Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 50,000 -- 69,048
Dec 14, 2010
SVP Res and Dev Sciences
SVP Res and Dev Sciences Form 4/A Grant, award or other acquisition pursuant to Rule 16b-3(d) 50,000 -- 50,350

* Represents the number of non-derivative securities directly held. (I) Indicates that some (or all) of these shares are held indirectly.