Date Name Title Filing Type Shares Traded Price Total Held
Jan 05, 2005
SVP, PreclinDevel & Biomol Sci
SVP, PreclinDevel & Biomol Sci Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 50,000 -- 50,000
Dec 16, 2011
SVP Research and Development S
SVP Research and Development S Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 48,079 -- 48,079
Dec 14, 2010
SVP Res and Dev Sciences
SVP Res and Dev Sciences Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 46,736 -- 46,736
Dec 18, 2009
SVP Res and Dev Sciences
SVP Res and Dev Sciences Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 45,295 -- 45,295
Jan 05, 2005
SVP, PreclinDevel & Biomol Sci
SVP, PreclinDevel & Biomol Sci Form 4 Disposition to the issuer of issuer equity securities pursuant to Rule 16b-3(e) 45,200 -- --
Dec 17, 2008
SVP, Research & Devel Sciences
SVP, Research & Devel Sciences Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 44,048 -- 44,048
Jul 24, 2009
SVP Res and Dev Sciences
SVP Res and Dev Sciences Form 4 Payment of exercise price or tax liability by delivering or withholding securities incident to the receipt, exercise or vesting of a security issued in accordance with Rule 16b-3 42,154 $20.14 47,659
May 14, 2021
EVP Research and Development
EVP Research and Development Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 40,000 $179.13 64,280
May 14, 2021
EVP Research and Development
EVP Research and Development Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 40,000 -- 72,500
Feb 12, 2014
SVP Research and Development S
SVP Research and Development S Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 40,000 $21.25 64,391

* Represents the number of non-derivative securities directly held. (I) Indicates that some (or all) of these shares are held indirectly.