Date Name Title Filing Type Shares Traded Price Total Held
Feb 12, 2014
SVP Research and Development S
SVP Research and Development S Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 40,000 -- 80,295
Aug 28, 2012
SVP Research and Development S
SVP Research and Development S Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 40,000 $21.92 99,121
Aug 28, 2012
SVP Research and Development S
SVP Research and Development S Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 40,000 -- 55,438
Nov 05, 2015
EVP Research and Development
EVP Research and Development Form 4 Payment of exercise price or tax liability by delivering or withholding securities incident to the receipt, exercise or vesting of a security issued in accordance with Rule 16b-3 39,605 $567.63 53,377
Jun 18, 2012
SVP Res & Dev Sciences
SVP Res & Dev Sciences Form 4 Payment of exercise price or tax liability by delivering or withholding securities incident to the receipt, exercise or vesting of a security issued in accordance with Rule 16b-3 39,411 $115.29 98,032
Aug 21, 2023
EVP Research and Development
EVP Research and Development Form 4 Payment of exercise price or tax liability by delivering or withholding securities incident to the receipt, exercise or vesting of a security issued in accordance with Rule 16b-3 38,335 $833.39 64,765
Nov 20, 2012
SVP Res and Devel Sciences
SVP Res and Devel Sciences Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 37,500 $16.80 104,219
Nov 20, 2012
SVP Res and Devel Sciences
SVP Res and Devel Sciences Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 37,500 -- 14,548
Aug 06, 2014
SVP Research and Development S
SVP Research and Development S Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 35,000 $21.25 48,527
Aug 06, 2014
SVP Research and Development S
SVP Research and Development S Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 35,000 -- 45,295

* Represents the number of non-derivative securities directly held. (I) Indicates that some (or all) of these shares are held indirectly.