Date Name Title Filing Type Shares Traded Price Total Held
Mar 10, 2020
Director, President and Chief Scientific
Director, President and Chief Scientific Form 4 Open market or private sale of non-derivative or derivative security 7,250 $469.46 575,777
Mar 10, 2020
Director, President and Chief Scientific
Director, President and Chief Scientific Form 4 Open market or private sale of non-derivative or derivative security 5,531 $470.48 570,246
Mar 10, 2020
Director, President and Chief Scientific
Director, President and Chief Scientific Form 4 Open market or private sale of non-derivative or derivative security 5,258 $471.34 564,988
Mar 10, 2020
Director, President and Chief Scientific
Director, President and Chief Scientific Form 4 Open market or private sale of non-derivative or derivative security 10,270 $472.56 554,718
Mar 10, 2020
Director, President and Chief Scientific
Director, President and Chief Scientific Form 4 Open market or private sale of non-derivative or derivative security 8,024 $473.39 546,694
Mar 10, 2020
Director, President and Chief Scientific
Director, President and Chief Scientific Form 4 Open market or private sale of non-derivative or derivative security 7,060 $474.52 539,634
Mar 10, 2020
Director, President and Chief Scientific
Director, President and Chief Scientific Form 4 Open market or private sale of non-derivative or derivative security 4,223 $475.43 535,411
Mar 09, 2020
Director, President and Chief Scientific
Director, President and Chief Scientific Form 4 Payment of exercise price or tax liability by delivering or withholding securities incident to the receipt, exercise or vesting of a security issued in accordance with Rule 16b-3 50,545 $476.42 563,990
Mar 09, 2020
Director, President and Chief Scientific
Director, President and Chief Scientific Form 4 Payment of exercise price or tax liability by delivering or withholding securities incident to the receipt, exercise or vesting of a security issued in accordance with Rule 16b-3 78,376 $476.42 635,614
Mar 10, 2020
Director, President and Chief Scientific
Director, President and Chief Scientific Form 4 Open market or private sale of non-derivative or derivative security 7,197 $476.51 528,214

* Represents the number of non-derivative securities directly held. (I) Indicates that some (or all) of these shares are held indirectly.