Date Name Title Filing Type Shares Traded Price Total Held
Jul 27, 2020
Director, President and Chief Scientific
Director, President and Chief Scientific Form 4 Bona fide gift 57,465 -- --
Mar 11, 2020
Director, President and Chief Scientific
Director, President and Chief Scientific Form 4 Other acquisition or disposition -- -- 57,465
Mar 11, 2020
Director, President and Chief Scientific
Director, President and Chief Scientific Form 4 Other acquisition or disposition -- -- 500,000
Mar 11, 2020
Director, President and Chief Scientific
Director, President and Chief Scientific Form 4 Other acquisition or disposition -- -- 5,791
Mar 10, 2020
Director, President and Chief Scientific
Director, President and Chief Scientific Form 4 Open market or private sale of non-derivative or derivative security 1,159 $461.79 634,455
Mar 10, 2020
Director, President and Chief Scientific
Director, President and Chief Scientific Form 4 Open market or private sale of non-derivative or derivative security 3,317 $462.43 631,138
Mar 10, 2020
Director, President and Chief Scientific
Director, President and Chief Scientific Form 4 Open market or private sale of non-derivative or derivative security 5,463 $463.54 625,675
Mar 10, 2020
Director, President and Chief Scientific
Director, President and Chief Scientific Form 4 Open market or private sale of non-derivative or derivative security 5,099 $464.59 620,576
Mar 10, 2020
Director, President and Chief Scientific
Director, President and Chief Scientific Form 4 Open market or private sale of non-derivative or derivative security 7,068 $465.45 613,508
Mar 10, 2020
Director, President and Chief Scientific
Director, President and Chief Scientific Form 4 Open market or private sale of non-derivative or derivative security 11,916 $466.58 601,592

* Represents the number of non-derivative securities directly held. (I) Indicates that some (or all) of these shares are held indirectly.