Date Name Title Filing Type Shares Traded Price Total Held
Jun 21, 2021
Director, President and Chief Scientific
Director, President and Chief Scientific Form 4 Open market or private sale of non-derivative or derivative security 3,306 $539.66 42,908
Jun 21, 2021
Director, President and Chief Scientific
Director, President and Chief Scientific Form 4 Open market or private sale of non-derivative or derivative security 8,099 $540.61 34,809
Jun 21, 2021
Director, President and Chief Scientific
Director, President and Chief Scientific Form 4 Open market or private sale of non-derivative or derivative security 19,911 $541.44 14,898
Jun 21, 2021
Director, President and Chief Scientific
Director, President and Chief Scientific Form 4 Open market or private sale of non-derivative or derivative security 10,514 $542.43 4,384
Jun 21, 2021
Director, President and Chief Scientific
Director, President and Chief Scientific Form 4 Open market or private sale of non-derivative or derivative security 2,276 $543.13 2,108
Apr 15, 2021
Director, President and Chief Scientific
Director, President and Chief Scientific Form 4 Bona fide gift 14,000 -- 14,000
Apr 15, 2021
Director, President and Chief Scientific
Director, President and Chief Scientific Form 4 Bona fide gift 14,000 -- --
Apr 15, 2021
Director, President and Chief Scientific
Director, President and Chief Scientific Form 4 Bona fide gift 5,383 -- --
Apr 15, 2021
Director, President and Chief Scientific
Director, President and Chief Scientific Form 4 Bona fide gift 5,383 -- 5,383
Jan 12, 2021
Director, President and Chief Scientific
Director, President and Chief Scientific Form 4 Bona fide gift 82,108 -- 82,108

* Represents the number of non-derivative securities directly held. (I) Indicates that some (or all) of these shares are held indirectly.