Date Name Title Filing Type Shares Traded Price Total Held
Aug 13, 2015
SVP Clinical Development & Reg
SVP Clinical Development & Reg Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 23,000 $52.03 46,299
Aug 13, 2015
SVP Clinical Development & Reg
SVP Clinical Development & Reg Form 4 Payment of exercise price or tax liability by delivering or withholding securities incident to the receipt, exercise or vesting of a security issued in accordance with Rule 16b-3 2,065 $579.35 44,234
Aug 13, 2015
SVP Clinical Development & Reg
SVP Clinical Development & Reg Form 4 Payment of exercise price or tax liability by delivering or withholding securities incident to the receipt, exercise or vesting of a security issued in accordance with Rule 16b-3 10,795 $579.35 33,439
Aug 13, 2015
SVP Clinical Development & Reg
SVP Clinical Development & Reg Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 8,000 $52.03 41,439
Aug 13, 2015
SVP Clinical Development & Reg
SVP Clinical Development & Reg Form 4 Payment of exercise price or tax liability by delivering or withholding securities incident to the receipt, exercise or vesting of a security issued in accordance with Rule 16b-3 718 $579.35 40,721
Aug 13, 2015
SVP Clinical Development & Reg
SVP Clinical Development & Reg Form 4 Payment of exercise price or tax liability by delivering or withholding securities incident to the receipt, exercise or vesting of a security issued in accordance with Rule 16b-3 3,755 $579.35 36,966
Aug 13, 2015
SVP Clinical Development & Reg
SVP Clinical Development & Reg Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 4,736 $30.63 41,702
Aug 13, 2015
SVP Clinical Development & Reg
SVP Clinical Development & Reg Form 4 Payment of exercise price or tax liability by delivering or withholding securities incident to the receipt, exercise or vesting of a security issued in accordance with Rule 16b-3 250 $579.35 41,452
Aug 13, 2015
SVP Clinical Development & Reg
SVP Clinical Development & Reg Form 4 Payment of exercise price or tax liability by delivering or withholding securities incident to the receipt, exercise or vesting of a security issued in accordance with Rule 16b-3 2,146 $579.35 39,306
Aug 13, 2015
SVP Clinical Development & Reg
SVP Clinical Development & Reg Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 4,736 -- --

* Represents the number of non-derivative securities directly held. (I) Indicates that some (or all) of these shares are held indirectly.