Date Name Title Filing Type Shares Traded Price Total Held
Jan 02, 2015
SVP Clinical Development & Reg
SVP Clinical Development & Reg Form 4 Open market or private sale of non-derivative or derivative security 1,642 $415.20 12,911
Jan 02, 2015
SVP Clinical Development & Reg
SVP Clinical Development & Reg Form 4 Open market or private sale of non-derivative or derivative security 900 $416.75 12,011
Jan 02, 2015
SVP Clinical Development & Reg
SVP Clinical Development & Reg Form 4 Open market or private sale of non-derivative or derivative security 1,000 $417.44 11,011
Jan 02, 2015
SVP Clinical Development & Reg
SVP Clinical Development & Reg Form 4 Open market or private sale of non-derivative or derivative security 300 $418.40 10,711
Dec 31, 2014
SVP Clinical Development & Reg
SVP Clinical Development & Reg Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 25,000 $52.03 35,711
Dec 31, 2014
SVP Clinical Development & Reg
SVP Clinical Development & Reg Form 4 Payment of exercise price or tax liability by delivering or withholding securities incident to the receipt, exercise or vesting of a security issued in accordance with Rule 16b-3 3,151 $412.78 32,560
Dec 31, 2014
SVP Clinical Development & Reg
SVP Clinical Development & Reg Form 4 Payment of exercise price or tax liability by delivering or withholding securities incident to the receipt, exercise or vesting of a security issued in accordance with Rule 16b-3 11,027 $412.78 21,533
Dec 31, 2014
SVP Clinical Development & Reg
SVP Clinical Development & Reg Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 25,000 -- 37,079
Dec 22, 2014
SVP Clinical Development & Reg
SVP Clinical Development & Reg Form 4 Other acquisition or disposition -- -- 18,000
Dec 22, 2014
SVP Clinical Development & Reg
SVP Clinical Development & Reg Form 4 Other acquisition or disposition -- -- 1,621

* Represents the number of non-derivative securities directly held. (I) Indicates that some (or all) of these shares are held indirectly.