Date Name Title Filing Type Shares Traded Price Total Held
May 24, 2019
Director, Chairman of the Board
Director, Chairman of the Board Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 153,792 -- 153,793
Jul 09, 2018
Director, Chairman of the Board
Director, Chairman of the Board Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 153,274 $16.80 553,121
Jul 09, 2018
Director, Chairman of the Board
Director, Chairman of the Board Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 153,274 -- --
Jun 20, 2018
Director, Chairman of the Board
Director, Chairman of the Board Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 153,274 $16.80 553,121
Jun 20, 2018
Director, Chairman of the Board
Director, Chairman of the Board Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 153,274 -- 153,274
Aug 26, 2014
Director, Chairman of the Board
Director, Chairman of the Board Form 4 Payment of exercise price or tax liability by delivering or withholding securities incident to the receipt, exercise or vesting of a security issued in accordance with Rule 16b-3 151,537 $351.62 390,852
Feb 19, 2019
Director, President and CSO
Director, President and CSO Form 4 Bona fide gift 150,722 -- 249,278
Feb 19, 2019
Director, President and CSO
Director, President and CSO Form 4 Bona fide gift 150,722 -- 753,316
Mar 09, 2020
Director, President and Chief Scientific
Director, President and Chief Scientific Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 150,000 -- --
Mar 09, 2020
Director, President and Chief Scientific
Director, President and Chief Scientific Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 150,000 $30.63 713,990

* Represents the number of non-derivative securities directly held. (I) Indicates that some (or all) of these shares are held indirectly.