Date Name Title Filing Type Shares Traded Price Total Held
Feb 28, 2008
Director
Director Form 4 Other acquisition or disposition -- -- 147,505
Dec 19, 2007
Director
Director Form 4 Other acquisition or disposition -- -- 147,505
Jun 29, 2007
Director
Director Form 4 Other acquisition or disposition -- -- 147,505
Jun 20, 2007
Director
Director Form 4 Other acquisition or disposition (describe transaction) 72,296 -- 147,505
Nov 22, 2011
Director
Director Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 15,000 $28.81 147,772
Aug 04, 2022
EVP Research and Development
EVP Research and Development Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 95,000 $270.43 147,795
Aug 21, 2018
Director, Chairman of the Board
Director, Chairman of the Board Form 4 Other acquisition or disposition -- -- 147,934
Jul 06, 2018
Director, Chairman of the Board
Director, Chairman of the Board Form 4 Bona fide gift 610 -- 147,934
Oct 28, 2014
Director, President & CEO
Director, President & CEO Form 4 Open market or private sale of non-derivative or derivative security 12,322 $400.52 148,147
Apr 02, 2018
Director, Chairman of the Board
Director, Chairman of the Board Form 4 Bona fide gift 616 -- 148,544

* Represents the number of non-derivative securities directly held. (I) Indicates that some (or all) of these shares are held indirectly.