Date Name Title Filing Type Shares Traded Price Total Held
Sep 06, 2011
VP Regulatory Development and
VP Regulatory Development and Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 1,685 -- --
Sep 06, 2011
VP Regulatory Development and
VP Regulatory Development and Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 4,512 -- 9,025
Sep 06, 2011
VP Regulatory Development and
VP Regulatory Development and Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 4,512 -- 4,513
Sep 06, 2011
VP Regulatory Development and
VP Regulatory Development and Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 4,513 -- --
Sep 06, 2011
Director, CEO & President
Director, CEO & President Form 4 Conversion of derivative security 7,000 -- 7,000
Sep 06, 2011
Director, CEO & President
Director, CEO & President Form 4 Conversion of derivative security 7,000 -- 22,275
Sep 06, 2011
SVP Research and Development S
SVP Research and Development S Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 82,818 -- --
Sep 02, 2011
VP Strategy and Investor Relat
VP Strategy and Investor Relat Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 4,166 -- 16,664
Sep 02, 2011
Director, Chairman of the Board
Director, Chairman of the Board Form 4 Other acquisition or disposition -- -- 2,271
Sep 02, 2011
Director, Chairman of the Board
Director, Chairman of the Board Form 4 Other acquisition or disposition -- -- 175,056

* Represents the number of non-derivative securities directly held. (I) Indicates that some (or all) of these shares are held indirectly.