Date Name Title Filing Type Shares Traded Price Total Held
Dec 16, 2004
Director
Director Form 4 Other acquisition or disposition -- -- 200,000
Jun 28, 2004
Director
Director Form 4 Other acquisition or disposition -- -- 200,000
Jun 21, 2004
Director
Director Form 4 Other acquisition or disposition -- -- 200,000
May 19, 2004
Director
Director Form 4 Other acquisition or disposition -- -- 200,000
May 17, 2004
Director
Director Form 4 Bona fide gift 200,000 -- 200,000
Jan 06, 2004
Director
Director Form 5 Other acquisition or disposition -- -- 200,000
Dec 17, 2003
Director
Director Form 4 Other acquisition or disposition -- -- 200,000
Sep 17, 2003
Director, Chief Exec Officer & President
Director, Chief Exec Officer & President Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 125,000 $14.75 200,095
Mar 23, 2023
Director, President and Chief Scientific
Director, President and Chief Scientific Form 4 Open market or private sale of non-derivative or derivative security 122 $801.16 200,128
Mar 23, 2023
Director, President and Chief Scientific
Director, President and Chief Scientific Form 4 Open market or private sale of non-derivative or derivative security 254 $800.59 200,250

* Represents the number of non-derivative securities directly held. (I) Indicates that some (or all) of these shares are held indirectly.