Date Name Title Filing Type Shares Traded Price Total Held
Jul 10, 2008
Director
Director Form 4 Bona fide gift 14,493 -- 282,372
Dec 03, 2012
SVP Fin & Admin CFO Asst Secy
SVP Fin & Admin CFO Asst Secy Form 4 Bona fide gift 14,500 -- 69,227
Dec 03, 2012
SVP Fin & Admin CFO Asst Secy
SVP Fin & Admin CFO Asst Secy Form 4 Bona fide gift 14,500 -- 14,500
Jul 09, 2014
Ten Percent Owner
Ten Percent Owner Form 4 Open market or private purchase of non-derivative or derivative security 14,532 $307.22 21,462,959
Dec 18, 2009
SVP Clinical Development
SVP Clinical Development Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 14,543 -- 14,543
May 21, 2020
Director, Chairman of the Board
Director, Chairman of the Board Form 4 Open market or private sale of non-derivative or derivative security 14,548 $566.42 346,675
Jul 09, 2014
Ten Percent Owner
Ten Percent Owner Form 4 Open market or private purchase of non-derivative or derivative security 14,586 $308.19 21,477,545
Aug 13, 2015
SVP Clinical Development & Reg
SVP Clinical Development & Reg Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 14,625 $179.13 33,030
Aug 13, 2015
SVP Clinical Development & Reg
SVP Clinical Development & Reg Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 14,625 -- 29,250
Dec 16, 2013
SVP Clinical Development & Reg
SVP Clinical Development & Reg Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 14,625 $179.13 38,503

* Represents the number of non-derivative securities directly held. (I) Indicates that some (or all) of these shares are held indirectly.