Date Name Title Filing Type Shares Traded Price Total Held
Dec 17, 2008
SVP, Clinical Development
SVP, Clinical Development Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 15,000 -- 15,000
Dec 17, 2008
VP, Regul Devel & Med Safety
VP, Regul Devel & Med Safety Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 5,952 -- 5,952
Dec 17, 2008
VP, Regul Devel & Med Safety
VP, Regul Devel & Med Safety Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 24,048 -- 24,048
Dec 17, 2008
Director, President & CEO
Director, President & CEO Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 187,500 -- 312,500
Dec 17, 2008
Director, Chief Exec Officer & President, Ten Percent Owner
Director, Chief Exec Officer & President, Ten Percent Owner Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 125,000 -- 125,000
Dec 17, 2008
SVP, Research & Devel Sciences
SVP, Research & Devel Sciences Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 5,952 -- 5,952
Dec 17, 2008
SVP, Research & Devel Sciences
SVP, Research & Devel Sciences Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 44,048 -- 44,048
Dec 17, 2008
SVP, Commercial
SVP, Commercial Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 5,952 -- 5,952
Dec 17, 2008
SVP, Commercial
SVP, Commercial Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 26,548 -- 26,548
Dec 17, 2008
Director
Director Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 5,952 -- 5,952

* Represents the number of non-derivative securities directly held. (I) Indicates that some (or all) of these shares are held indirectly.